Life Science Leader Magazine

FEB 2014

The vision of Life Science Leader is to be an essential business tool for life science executives. Our content is designed to not only inform readers of best practices, but motivate them to implement those best practices in their own businesses.

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Exclusive Life Science Feature W W hen I sat down with Eli Lilly (NYSE: LLY) and Company's chief medical officer and coleader of the company's Development Center of Excellence, Timothy Garnett, it was shortly after the drugmaker's annual investment community meeting where bankers grilled the leadership team with questions. Although sensationalistic headlines of Lilly's recent Phase 3 trial failures (e.g. the antidepressant edivoxetine) may have attracted the eyes of the uneducated, those of us in the industry know that long-term success in drug development — like investing — requires patience and perseverance. That's why it should come as no surprise that when I asked Garnett what he is doing to speed up clinical trials he responded, "Sometimes you have to slow down in order to speed up." Indeed, a counterintuitive notion when you consider Lilly will be losing patent exclusivity for another one of its blockbusters, Evista, this March. Yet during our interview Garnett, a 20+ year industry veteran, made a strong case for following this paradox (slowing down to speed up) if improved productivity and performance is your goal. SLOW DOWN TO SPEED UP Businesses fearful of losing their competitive advantage make the common mistake of spending too much time and resources seeking ways to pick up the pace, when instead they should try slowing down. Here's why. A Harvard Business Review (HBR) study of 343 businesses revealed that companies that embraced business-accelerating initiatives in order to gain an edge ended up with lower sales and operating profits than those pausing at key moments. Firms that "slowed down to speed up" improved their top and bottom lines, averaging 40 percent higher sales and 52 percent higher operating profits over a three-year period. These findings appeal to Garnett who revealed Lilly's average lifetime development cycle for a molecule is about six months longer than the industry average of 12 years. The company wants to shorten its clinical development February 2014 LifeScienceLeader.com 27

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