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CMO Leadership Awards 2013

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Contract Manufacturing Roundtable sustainability initiative does not impact the final quality, then I am entirely for it. Keltner: I don't believe sustainability initiatives have anything at all to do with OPEX. They are simply politically necessary and so have to be logically included in corporate and campaign planning. CMOs need to be aware of both the regulations and hot buttons in sustainability and be able to balance the inevitable additional cost with the costs of legal actions or bad PR. This is not to say that sustainability initiatives are bad — they are just quite separate from efficient drug manufacturing. Kempinski: With cost-reduction pressures, it may seem attractive to take short-term decisions to reduce/delay spending in areas such as training or waste management, or select a supplier based on cost; unfortunately, all can lead to long-term challenges that work against OPEX objectives. Sustainability initiatives can broadly impact social, economic, and environmental outcomes for players across the supply chain. CMOs could follow the route of the Pharmaceutical Supply Chain Initiative (PSCI) to establish an alliance for responsible supplier business and environmental practices. Examples of smaller initiatives I am aware of include the use of solvent recycling, movement to reusable packing and temperature monitoring devices, and the use of green power sources. O'Brien: In today's competitive business environment, the benefits of sustainability initiatives are key to improving business processes and operational efficiency. There are obvious cost savings that come from reducing energy and/or water consumption, all of which can contribute to company profitability. OPEX principles (continuous improvement, optimizing processes, etc) go hand in hand with sustainability initiatives. Be it developing new chemical entities or optimizing current processes, optimizing/minimizing such things as solvent volumes, reagent stoichiometries, reaction temperatures, processing times, and the like are critical. Similar sustainability initiatives, when employed by CMOs, can offer the same business benefits and a competitive advantage. In addition to the cost savings associated with continuously optimizing processes and reducing waste, CMOs are more likely to be regarded as highly ethical and a partner of choice. CMOs should embrace corporate sustainability and work closely with partner companies on these types of initiatives. For additional insights on this and other outsourcing topics, go to www.outsourcedpharma.com. expect more Innovation + Sustainability Siegfried combines innovation with sustainability Bringing together our long-standing pharma and chemical heritage, our customers benefit from our innovative approach of an integrated supplier with more synergy, expertise and value. A combination of know-how and experience that is unique for a supplier of development and manufacturing services. Expect more with Siegfried as your preferred partner Siegfried at CPhI Frankfurt 2013 You are most welcome to our booth 31H25/Hall 3.1 from October 22–24, 2013 Siegfried at AAPS You are most welcome to our booth spaces 3000 & 3001 from November 10–14, 2013 www.siegfried.ch The CMO Leadership Awards 2013 19

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