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L O U I S G A R G U I L O Executive Editor, Outsourced Pharma @Louis_Garguilo
ness performance management process."
We'll take a look at that process closely,
but in essence, Reliability Rooms started
in 2011 as, and still include, physical areas
established at each of the company's
20-plus manufacturing locations. Within
these rooms Janssen gathers an array
of supply chain metrics for finished
drug products and APIs, available for
cross-functional teams to review, digest
together, and take specific actions on.
A mainstay of that data for drug product
plants has been the LIFR mentioned ear-
lier. This can be defined as an overall
measure of the ratio of actual orders
filled in terms of all the fulfillment lines
for a product. For example, if three of
five lines of an order are filled, the LIFR
would be 60 percent. Looked at from the
90 percent reduction in missed orders
since 2011.
Colarusso, a 27-year veteran of J&J;, spoke
exclusively with Life Science Leader CMO
Supplement about a main driver of these
results. Below he describes how Janssen's
"Reliability Rooms" are elevating the art
of measuring and improving reliability
and quality throughout the supply chain.
And while some of this information
may prove valuable to other pharma
companies, external partners should take
equal notice — a "room" could be heading
your way soon.
Metrics To Build On
"Reliability Rooms aren't just a room and
a place," says Colarusso. "They're a busi-
emo Colarusso, VP, manufacturing
and technical operations at
Janssen (pharmaceutical com-
panies of Johnson & Johnson),
knows what you measure is as
important as how you measure,
and cross-functional review of the results
can be as essential as the results them-
selves. He also knows that nowadays,
Janssen appears in good shape in all four
of these quadrants.
For proof of this, Janssen, like other
pharma companies, looks to supply chain
measurements such as LIFRs — line item
fill rates (more on LIFR specifically in
a moment.) Executives at other phar-
mas might be envious of the statistics
Colarusso sees: obtaining or exceeding
99.5 percent LIFR for core products;
R
Reliability Rooms
Supply Chains
And
At Janssen